Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

Titanium dioxide can also be found in dairy products to make them whiter and brighter … like frosting or cottage cheese, Stoiber told USA TODAY, adding that the additive is used in other products – such as food or beverage instant mixes – as an anti-caking agent.

Barium sulphate is typically described as a white, odorless powder. This white coloration is due to its crystalline structure and the arrangement of Ba^2+ and SO₄^2− ions within the compound. The brightness and consistency of this white powder are crucial for its use in various applications. For instance, in the pharmaceutical industry, barium sulphate is used as a radiopaque agent in X-ray imaging of the gastrointestinal tract. In this context, its purity and the absence of color impurities are vital for ensuring accurate imaging results.

Nano-sized P25TiO₂NPs were kindly donated by Dr. Scaiano, Ottawa University (Canada). Riboflavin (vitamin B2) was from Sigma and ascorbic acid (vitamin C) and KBr (for IR pills) were from Cicarelli. Base cream for the animal experiments was purchased from Todo Droga and the LED panel was built ad hoc.

Applications

In their role as risk managers, the European Commission and Member States will now reflect on EFSA’s scientific advice and decide upon any appropriate regulatory measures or advice for consumers.

Titanium dioxide nanoparticles may accumulate and cause DNA damage

All samples (n = 6) were irradiated in a 96 well plate using an LED panel on top for 3 and 6 h before analysis. An identical set of samples were kept in the dark as controls. The temperature was checked and did not go over 37 °C. The intensity of light was also measured and was constant at 19,500.10 lux. (43.33 W in 0.2 m²), about 5 times less than actual solar light intensity on Earth's surface Therefore, these findings are indicative of even greater danger in real life.

A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

Lithopone Market 

Titanium dioxide is produced at pigment grade or nano grade.

China's titanium dioxide enterprises are currently in the stage of capacity expansion and upgrading. With the recovery of the world economy, Caiqing Technology seized the opportunity to occupy the market, titanium dioxide has been exported to more than 90 countries and regions, and has been recognized and unanimously praised by customers in the United States, Singapore, India, Saudi Arabia, Vietnam, Brazil, and other countries. Our company will continue to increase the research and development of titanium dioxide, and provide high-quality titanium dioxide for various industries around the world.