Most food-grade titanium dioxide is around 200–300 nanometers (nm) in diameter. This size allows for ideal light scattering, resulting in the best color (1Trusted Source).

Lithopone 30% CAS No. 1345-05-7 / Application

Further outstanding properties of Lithopone are its high lightness, neutral white colour and its diffuse reflectance in the near UV range.

Tint reducing power, compared with standard samples

A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

Breathing problems in offspring

The color of barium sulphate, predominantly white, plays a crucial role in its identification and application across various industries. With the demand for high-quality barium sulphate soaring, choosing the right supplier becomes vital. Businesses must consider factors like purity, particle size, regulatory compliance, and customer service when sourcing barium sulphate to ensure they receive a product that meets their stringent requirements. As industries continue to evolve, reliable suppliers will remain indispensable in providing the necessary materials to support innovations and advancements.